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What is It?

Since its approval in 1999, Avandia (rosiglitazone) is a medication prescribed for the treatment of Type 2 diabetes and is manufactured by pharma giant GlaxoSmithkline (GSK). This diabetes drug works by regulating insulin and controlling blood sugar in the body.

The Issue

A number of studies and reports indicate that the medication may not be effective and may cause significant health risks.

The New England Journal of Medicine reported that patients taking Avandia have over a 40% increased risk of heart attacks and a risk of death from heart related conditions.

In May 2007, a New York Times report on a study conducted by Dr. Steven Nissen of the Cleveland Clinic noted that Avandia raised the risk of heart attacks by 43% compared to other diabetes drugs or no medication.

In February 2008, the United States Government announced that it had decided to stop it ACCORD clinical trial of diabetes treatment as a result of an increased risk of patient’s death. A safety board monitoring the trial noted that intense treatment increased patient death risk up to 25%.

Other preliminary data provided to the FDA indicate that patients that use these medications on a short term basis (six months or less) demonstrate an increased risk of heart-related problems by 30 to 40 percent.


Mr. Sudekum and Mandel & Mandel, LLP, are currently reviewing cases where individuals have sustained:

  • Heart attack,
  • Congestive Heart Failure,
  • Stroke, and
  • Death.

If you or a loved one sustained injuries or death while taking Avandia, contact Avandia lawyer Mike Sudekum for more information.